Spot detectoion at the single cell level: A computational approach to analyse ifish spots in consecutive sections of heterogeneous neuroblastoma tumors
Autoren |
Magdalena Ambros Maria Berneder Lukas Fischer Marco Feuerstein Allan Hanbury Inge M. Ambros Peter F. Ambros Sabine Taschner-Mandl |
Editoren |
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Titel | Spot detectoion at the single cell level: A computational approach to analyse ifish spots in consecutive sections of heterogeneous neuroblastoma tumors |
Typ | sonst |
Ort | 15th YSA PhD Symposium, Vienna, Austria, June 113-14, 2019. |
Monat | June |
Jahr | 2019 |
Seiten | Poster |
Abstract | Interphase-fluorescence in situ hybridization (iFISH) is a robust and powerful method to detect chromosomal aberrations and rearrangements at single-cell resolution. Automated image analysis methods, based on iFISH spot detection at the single cell level, could help to better describe tumor heterogeneity. However, methods to segment spot- and nuclear images and to analyze spatially resolved single-cell features in tissue sections are still missing. |